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Kleh Lecture on Thursday 09 October

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You are cordially invited to this year’s Kleh Lecture. Dr. Edward Damiano, Associate Professor of Biomedical Engineering at BU will be delivering this year’s lecture on his groundbreaking work in the field of Diabetes. Please click this link to register.

Registration required. Seating is limited and early registration is encouraged.

Canapés and drinks at 6 p.m.

Lecture begins at 7 p.m. Boston Room @ 43 Harrington Gardens

For over 14 years, Ed Damiano would wake at night every two or three hours, steal into his son David’s bedroom, and check the boy’s blood sugar. If he’d overslept and missed his scheduled check, he would rush anxiously to David’s side and lay a hand on his body, feeling first for the warmth that told him his boy was all right. Join us on the family’s journey that led to the development BU’s Bionic Pancreas. Read more in Bostonia. Thursday, 9 October 2014

Dr. Damiano is an Associate Professor of Biomedical Engineering at Boston University. His expertise and training are in the areas of mechanical and biomedical engineering, applied mechanics, and applied mathematics. Ever since his 15-year-old son was diagnosed with type 1 diabetes at 11 months of age, he has been committed to creating and integrating closed-loop control technologies with a vision of building a bionic endocrine pancreas by the time his son heads off to college in the fall of 2017. This endeavor began with the design and development of mathematical algorithm strategies for blood glucose control, which he and his group began testing in his laboratory at Boston University in 2005 in a swine model of type 1 diabetes.

In 2006, he began working with his clinical collaborators at the Massachusetts General Hospital (MGH) to design their first clinical protocol. Between 2008 and 2012, they tested their system in the inpatient setting in one-day and two-day experiments in adults and adolescents with type 1 diabetes in the Clinical Research Center at the MGH. Near the end of 2012 they received approval from the FDA to begin testing a mobile version of their system, which integrates an iPhone with their blood-glucose control algorithm, an insulin pump, and a continuous glucose monitor. Between February and September 2013, they conducted an ambitious outpatient trial testing their bihormonal bionic pancreas in five-day experiments in 20 adult subjects with type 1 diabetes in downtown Boston. In the summers of 2013 & 2014, they conducted their Summer Camp Study testing their bihormonal bionic pancreas in five-day experiments in 32 adolescents and 19 pre-adolescents with type 1 diabetes at Camp Joslin and the Clara Barton Camp in central Massachusetts. The Results of the Beacon Hill Study and the 2013 Summer Camp Study were recently published in the New England Journal of Medicine.

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